Modern drugs has not been sort to Dr. Linus Pauling. He is the one individual to have obtained two unshared Nobel Prizes: one for Chemistry in 1954 and one for Peace in 1962. But it’s his analysis into vitamin C for most cancers and vitamin C for the frequent chilly that has disturbed most well being professionals. They have spent years making an attempt to dispute his enthusiasm for vitamin C.
Dr. Linus Pauling Gets Trashed:
The headlines have been ruthless:
A Vox Headline (Feb. 27, 2015) acknowledged:
“How Linus Pauling duped America into believing vitamin C cures colds”
The writer states unequivocally:
“…every thing we find out about analysis exhibits that mega-doses of vitamin C are completely, positively ineffective at combating colds. All that further orange juice will do nothing to shorten your sniffles.”
There are many extra experiences identical to that.
Nutrition consultants have insisted for many years that further vitamin C is a waste of cash. They keep that each one a girl wants is 75 mg day by day. Men have a really useful day by day allowance (RDA) of 90 mg.
What About Vitamin C for Cancer That is Hard to Treat?
If you suppose nutritionists have been arduous on Linus Pauling, most oncologists have been way more vital.
For instance, an article within the extremely regarded journal Science (Feb. 6, 2014) acknowledged this about Dr. Pauling’s work on vitamin C for most cancers: .
“His personal forays into the clinic with this concept had been embarrassing, and extra competently run trials (a number of of them) have failed to show up any profit.
“He was the true deal, and completed about 4 or 5 occasions as a lot as anybody would think about an excellent profession.
“But that makes it all of the extra unhappy to see what turned of him in his later years…I’d additionally heard of his relentless advocacy for Vitamin C, which progressively (or possibly not so progressively) prompted folks to suppose that he had barely misplaced his thoughts. Perhaps he had; there’s no approach of figuring out. But the best way he approached his Vitamin C work was a curious (and unhappy) combination of the identical boldness that had served him so nicely up to now, however now with a messianic pressure that will in all probability have confirmed deadly to a lot of his personal earlier work.”
Vitamin C for Cancer is a “Zombie Idea”:
Other researchers have been much more disdainful.
An article within the journal Science-Based Medicine (August 18, 2008) by Dr. David Gorski describes Dr. Pauling’s analysis into vitamin C for most cancers as “pseudoscience”:
“Treating most cancers with high-doses of vitamin C is a zombie concept that started with Linus Pauling, and has didn’t die ever since. But has new analysis vindicated this concept? No. No in any significant approach.”
Vindicating Linus Pauling:
Vitamin C for Colds:
You can learn my current article about vitamin C for colds at this link. Our eGuide on Colds, Coughs & the Flu additionally supplies extra data on vitamin C for higher respiratory tract infections at this link.
But please do not take my phrase for it. Here is an article within the journal Life (Jan. 3, 2022) by two scientists, one from Finland and the opposite from Australia. They appear much less prepared to trash vitamin C than their American colleagues. In reality, they appear fairly open-minded and prepared to look at the info about vitamin C for most cancers and colds. The title of their article is:
“Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections”
They introduce their overview this fashion:
“Evidence has proven unambiguously that, in sure contexts, vitamin C is efficient towards the frequent chilly. However, in mainstream drugs, the views on vitamin C and infections have been decided by eminence-based drugs relatively than evidence-based drugs…While most of our examples are from JAMA, it’s not the one journal with obvious bias towards vitamin C, however it illustrates the overall views in mainstream drugs. We additionally think about potential explanations for the widespread bias towards vitamin C.”
They go on to debate comparable biases towards vitamin C for most cancers:
“Our paper is primarily centered on vitamin C for infections, however we briefly touch upon the controversy about vitamin C and most cancers for 2 causes. Firstly, after his work on vitamin C and the frequent chilly, Pauling got interested within the results of vitamin C on most cancers. Secondly, there’s a complete sociological evaluation of the extreme biases within the evaluation of vitamin C’s results on most cancers.
“Over the many years because the Nineteen Eighties, the organic rationale for vitamin C for most cancers has not diminished; relatively, a rise in biochemical understanding has made scientific results much more believable.”
Conclusions:
“The perception that vitamin C is ‘ineffective’ towards the frequent chilly is widespread. For instance, a survey of basic practitioners within the Netherlands discovered that 47% of respondents thought-about that homeopathy is efficient towards the frequent chilly, however simply 20% of the respondents thought-about that vitamin C was efficient. Given the wide selection of demonstrated biochemical results of vitamin C, a lot of which have been recognized for greater than half a century, and the advantages noticed in quite a few placebo-controlled trials within the Seventies, it’s regarding that so few basic practitioners believed vitamin C to be efficient; but, that’s what the survey discovered. This is one illustration of how deeply physicians have been influenced by the flawed displays of the vitamin C area in textbooks and main journals.
“This bias is unlucky as a result of vitamin C is secure and cheap, and due to this fact even fairly small remedy results are nicely price taking into account.”
Vitamin C for Cancer: New Evidence!
A research printed in Redox Biology (November, 2024) is titled:
“A randomized trial of pharmacological ascorbate, gemcitabine, and nab-paclitaxel for metastatic pancreatic most cancers”
Researchers on the University of Iowa carried out a randomized scientific trial of high-dose intravenous vitamin C to deal with stage IV metastatic pancreatic most cancers. The ascorbic acid was given together with customary remedy and the management group bought customary remedy solely.
The outcomes had been so promising that the investigators stopped the trial early. Vitamin C doubled common survival time from 8 months to 16 months. The lead investigator added that sufferers appeared to really feel higher when vitamin C was added to the routine.
Not the First Study of Vitamin C for Cancer:
These are strong researchers. Dr. Joseph Cullen is a professor of Surgery and Radiation Oncology on the University of Iowa. One of his colleagues, Bryan Allen, MD, PhD, is professor and chief of Radiation Oncology on the University of Iowa. They and plenty of colleagues have been learning the consequences of high-dose vitamin C for hard-to-treat cancers over the past twenty years.
Dr. Cullen informed StudyFinds (December 1, 2024):
“Through each step of the method, it continued to enhance. We did it in cells, it labored nice. We did it in mice, it labored nice. Then our part one trials regarded very promising. So, the development has simply been phenomenal, actually. For instance, in one in every of our part 1 trials for pancreatic most cancers, the place we mix high-dose IV vitamin C with radiation, we nonetheless have three long-term survivors. They’re out 9 years at this level, which is way past the standard survival vary.”
This staff of investigators reported on a research of high-dose vitamin C (ascorbate) in glioblastoma sufferers. This form of mind most cancers is particularly lethal. When IV vitamin C is added to radiation and chemotherapy, survival can be improved.
Here is how they and their colleagues describe their vitamin C (ascorbate) analysis (International Journal of Molecular Sciences, Oct. 8, 2021):
First, they acknowledge the important thing position of Dr. Linus Pauling and his colleague, Dr. Ewan Cameron, in creating intravenous vitamin C remedy for difficult cancers:
“This analysis has produced promising outcomes for among the most aggressive most cancers sorts together with glioblastoma (GBM), non-small cell lung most cancers (NSCLC), and pancreatic most cancers. Historically, these aggressive cancers reply poorly to radiation and chemoradiation remedy approaches, accentuating the necessity to discover different and adjuvant therapies like P-AscH−[high-dose Vitamin C].”
“Interest in the usage of pharmacological ascorbate as a remedy for most cancers has elevated significantly because it was launched by Cameron and Pauling within the Seventies. Recently, pharmacological ascorbate has been utilized in preclinical and early-phase scientific trials as a selective radiation sensitizer in most cancers. The outcomes of those research are promising. This assessment summarizes knowledge on pharmacological ascorbate (1) as a secure and efficacious adjuvant to most cancers remedy; (2) as a selective radiosensitizer of most cancers by way of a mechanism involving hydrogen peroxide; and (3) as a radioprotector in regular tissues. Additionally, we current new knowledge demonstrating the flexibility of pharmacological ascorbate to reinforce radiation-induced DNA harm in glioblastoma cells, facilitating most cancers cell dying. We suggest that pharmacological ascorbate could also be a basic radiosensitizer in most cancers remedy and concurrently a radioprotector of regular tissue.”
The backside line appears to be that some hard-to-treat cancers typically reply surprisingly nicely to high-dose intravenous vitamin C. The Iowa investigators point out glioblastoma, sarcoma, pancreatic most cancers and non-small cell lung most cancers (NSCLC).
Vitamin C for Cancers in Women:
A research printed within the journal Antioxidants (May 19, 2024) experiences that intravenous vitamin C generally is a highly effective addition to most cancers therapies:
“Until the top of the twentieth century and with a deepening understanding of the distribution of pharmacokinetics, ascorbate was discovered to inhibit most cancers cell proliferation and tumor progress in nearly all preclinical fashions with out apparent uncomfortable side effects when the concentrations of ascorbate reached the degrees of millimoles, known as high-dose ascorbate. Over the previous three many years, research on the antineoplastic results of ascorbate as a single agent or together with different chemotherapeutic brokers have grown considerably in numerous cancers, together with gynecological cancers. These outcomes point out that high-dose ascorbate reveals potent antitumor exercise, in addition to synergy with chemotherapeutic medicine in numerous cell and animal fashions of most cancers.”
Conclusions:
“High-dose ascorbate has been proven to be a possible therapeutic agent that inhibits cell proliferation, reduces invasive capability, and acts synergistically with chemotherapeutic brokers in preclinical fashions of ovarian, endometrial, and cervical cancers.”
Final Words on Vitamin C for Cancer and Colds:
Dr. Linus Pauling was a genius. He can’t rise from the grave so I’ll say it for him:
“I Told You So!”
Despite the naysayers, vitamin C analysis has continued. Although mainstream drugs appears to need to bury this “zombie” nutrient, it retains rising from the grave.
If researchers proceed to comply with up on Dr. Linus Pauling’s analysis, they may be shocked to find that vitamin C has certainly lived as much as his expectations.
What is your expertise with vitamin C? Please share your ideas within the remark part beneath. If you suppose this text was worthwhile, please share it with household and pals.
We could be grateful when you inspired them to enroll in our publication at this link. Where else may you get such an in-depth and impartial evaluation of vitamin C? If you wish to help our efforts to proceed to maintain you knowledgeable, here is a link.
